WKYMVm

£75.00 1mg

FPR1, FPR2 and FPR3 receptor agonist.

WKYMVm is a selective agonist for formyl peptide receptors FPR1, FPR2 (EC50 = 75 pM) and FPR3 (EC50 = 3 nM) when expressed on immune cells. WKYMVm induces Ca2+ mobilization and superoxide production in, and chemotaxic migration of, monocytes and neutrophils. WKYMVm has pleiotropic anti-inflammatory, pro-angiogenic, anti-apoptotic and immunomodulatory effects in various animal models of sepsis, ulcerative colitis, myocardial infarction, ischemic hindlimb and diabetic cutaneous wound healing.

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SKU: FR-010 Categories: ,

Additional information

Other Names

Leukocyte chemoattractant peptide

Three Letter Sequence

H-Trp-Lys-Tyr-Met-Val-D-Met-NH2

Molecular Weight

856.11

Molecular Formula

C41H61N9O7S2

Sequence

WKYMVm-NH2

Solubility

Soluble to 2 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

Methionine 6 is D-Met, C-terminal amide

Searchable Words

WKYMVm, 187986-17-0, Leukocyte chemoattractant peptide, FR-010