Tiger17

£145.00 1mg

Potent healer of skin wounds.

Tiger17 is an 11 amino acid peptide with a disulphide bridge between cysteines 2 and 10, which is a potent healer of skin wounds. Tiger17 was designed based on the antimicrobial peptides tigerinin-RC1 and tigerinin RC2, identified from the skin secretions of the crab eating frog Fejervarya cancrivora which also exert wound healing activity. Tiger17 exerts significant effects at various stages of wound healing progresses – the induction of macrophage recruitment to the wound site at the inflammatory reaction stage, the promotion of migration and proliferation of keratinocytes and fibroblasts, and at the tissue remodeling phase. In mouse models Tiger17 accelerates the healing of full-thickness wounds and promotes re-epithelialization of skin wounds.

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SKU: IM-030 Categories: ,

Additional information

Three Letter Sequence

H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2, disulphide bridge between cysteines 2 and 10

Molecular Weight

1377.69

Molecular Formula

C62H96N20O12S2

Sequence

WCKPKPKPRCH-NH2

Solubility

Soluble in DMSO as stock and physiological buffers

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Modifications

Contains a disulphide bridge between cysteines 2 and 10

Searchable Words

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