TAT-AKAP79 (326-336)
£145.00 1mg
The key region of AKAP79 for interaction with TRPV1.
TAT-AKAP79 (326-336) is amino acids 326 336 of A-kinase anchoring protein 79 (AKAP79), the human anchoring protein, fused to TAT to promote uptake across the cell membrane. AKAP79 (326-336) is the key region of AKAP79 for interaction with transient receptor potential vanilloid 1 (TRPV1), the thermo-TRP ion channel activated by painful levels of heat, and AKAP79 binding to TRPV1 blocks TRPV1 sensitization. TAT-AKAP79 (326-336) inhibits inflammatory hyperalgesia in mice.
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Additional information
| Three Letter Sequence | H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Ser-Lys-Ser-Glu-Glu-Ser-Lys-Arg-Met-Glu-OH |
|---|---|
| Molecular Weight | 2880.34 |
| Molecular Formula | C117H211N49O34S1 |
| Sequence | YGRKKRRQRRRKSKSEESKRME |
| Solubility | Soluble in DMSO |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | TAT-AKAP79 (326-336), H-YGRKKRRQRRRKSKSEESKRME-OH, YGRKKRRQRRRKSKSEESKRME, A-kinase anchoring protein 79, AKAP79, transient receptor potential vanilloid 1 , TRPV1, hyperalgesia in mice, PP-130 |