TAT-AKAP79 (326-336)

£145.00 1mg

The key region of AKAP79 for interaction with TRPV1.

TAT-AKAP79 (326-336) is amino acids 326 336 of A-kinase anchoring protein 79 (AKAP79), the human anchoring protein, fused to TAT to promote uptake across the cell membrane. AKAP79 (326-336) is the key region of AKAP79 for interaction with transient receptor potential vanilloid 1 (TRPV1), the thermo-TRP ion channel activated by painful levels of heat, and AKAP79 binding to TRPV1 blocks TRPV1 sensitization. TAT-AKAP79 (326-336) inhibits inflammatory hyperalgesia in mice.

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SKU: PP-130 Categories: ,

Additional information

Three Letter Sequence

H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Ser-Lys-Ser-Glu-Glu-Ser-Lys-Arg-Met-Glu-OH

Molecular Weight

2880.34

Molecular Formula

C117H211N49O34S1

Sequence

YGRKKRRQRRRKSKSEESKRME

Solubility

Soluble in DMSO

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

TAT-AKAP79 (326-336), H-YGRKKRRQRRRKSKSEESKRME-OH, YGRKKRRQRRRKSKSEESKRME, A-kinase anchoring protein 79, AKAP79, transient receptor potential vanilloid 1 , TRPV1, hyperalgesia in mice, PP-130