SLIGRL-NH2
£75.00 1mg
PAR2 activating peptide.
SLIGRL-NH2 is an agonist peptide derived from the N-terminus (aas 39-44) of protease-activated receptor 2 (PAR2). SLIGRL-NH2 activates PAR2 with an EC50 of approximately 5 μM and through its effects on PAR2 it stimulates gastric and intestinal smooth muscle contraction. SLIGRL-NH2 is a pruritogen and causes scratching behaviour in mice.
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Additional information
| Other Names | PAR-2 activation peptide, SL-NH2 |
|---|---|
| Three Letter Sequence | H-Ser-Leu-Ile-Gly-Arg-Leu-NH2 |
| Molecular Weight | 656.82 |
| Molecular Formula | C29H56N10O7 |
| Sequence | SLIGRL-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C-terminal amide |
| Searchable Words | SLIGRL-NH2, 171436-38-7 |