SLIGRL-NH2
£75.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
PAR2 activating peptide.
SLIGRL-NH2 is an agonist peptide derived from the N-terminus (aas 39-44) of protease-activated receptor 2 (PAR2). SLIGRL-NH2 activates PAR2 with an EC50 of approximately 5 μM and through its effects on PAR2 it stimulates gastric and intestinal smooth muscle contraction. SLIGRL-NH2 is a pruritogen and causes scratching behaviour in mice.
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Additional information
| Other Names | PAR-2 activation peptide, SL-NH2 |
|---|---|
| Three Letter Sequence | H-Ser-Leu-Ile-Gly-Arg-Leu-NH2 |
| Molecular Weight | 656.82 |
| Molecular Formula | C29H56N10O7 |
| Sequence | SLIGRL-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C-terminal amide |
| Searchable Words | SLIGRL-NH2, 171436-38-7 |