SLIGKV-NH2

£55.00 1mg

Protease activated receptor 2 (PAR2) agonist.

SLIGKV-NH2 is a protease-activated receptor 2 (PAR2) agonist with a Ki of 9.64 μM and an IC50 of 10.4 μM. SLIGKV-NH2 corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2 and like other peptides corresponding to the tethered ligand sequences of the thrombin receptor and PAR-2 receptor is a full agonist and can be used to investigate receptor function. SLIGKV-NH2 stimulates lactoferrin and IL-8 secretion from human neutrophils.

Please contact us for availability.

SKU: PR-060 Categories: ,

Additional information

Three Letter Sequence

H-Ser-Leu-Ile-Gly-Lys-Val-NH2

Molecular Weight

614.78

Molecular Formula

C28H54N8O7

Sequence

SLIGKV-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

C-terminal amide)

Searchable Words

SLIGKV-NH2, 190383-13-2