SFFLRN-NH2

£85.00 1mg

Protease activated receptor-1 (PAR-1) activator.

SFFLRN-NH2 is the tethered ligand domain sequence of murine protease-activated receptor-1 (PAR-1), the G protein-coupled receptor highly expressed in platelets and endothelial cells and one of four protease-activated receptors involved in the regulation of the thrombotic response. SFFLRN-NH2 activates PAR-1 and induces relaxant responses of mouse isolated tracheal smooth muscle preparations which are mediated by prostaglandins.

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SKU: PR-110 Categories: ,

Additional information

Other Names

SFLLRN-amide

Three Letter Sequence

H-Ser-Phe-Phe-Leu-Arg-Asn-NH2

Molecular Weight

781.9

Molecular Formula

C37H55N11O8

Sequence

SFFLRN-NH2

Solubility

Soluble in water to 1mg per ml

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Modifications

C terminal amide

Searchable Words

SFFLRN-amide, thrombin receptor agonist peptide, SFFLRN-NH2, tethered ligand domain sequence of murine protease-activated receptor-1, PAR-1, H-SFFLRN-NH2, PR-110