[Pyr1]-Apelin 13

£55.00 1mg

Endogenous agonist for the apelin APJ receptor.

[Pyr1]-Apelin 13 or [pGlu1]-apelin-13 is a highly potent pyroglutamyl form of apelin 13 which acts as the endogenous ligand for the apelin APJ receptor, with an EC50 of 0.37 nM. [Pyr1]-Apelin 13 is the predominant isoform detected in human heart and plasma and acts as a potent inotropic agent and vasodilator.

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SKU: AR-020 Categories: ,

Additional information

Other Names

[Pyr1]-Apelin 13, [pGlu1]-apelin-13

Three Letter Sequence

Glp-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH

Molecular Weight

1533.8

Molecular Formula

C69H109N22O16S

Sequence

XRPRLSHKGPMPF

Solubility

Soluble in dilute acid and physiological buffers

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

X is pGlu

Searchable Words

[Pyr1]-Apelin 13, [pGlu1]-apelin-13, pyroglutamyl, endogenous, apelin APJ receptor, 217082-60-5, Glp-RPRLSHKGPMPF-OH, Glp-RPRLSHKGPMPF, AR-020