Pepstatin A

£65.00 1mg

SKU: PI-120 Categories: ,

Aspartyl peptidase inhibitor.

Pepstatin A is an inhibitor of aspartyl peptidases. Pepstatin A is highly selective for proteases such as pepsin, renin, cathepsin D, bovine chymosin, and protease B and does not inhibit thiol proteases, neutral proteases, or serine proteases. Pepstatin A also inhibits solubilized ?-secretase and retroviral proteases and has been used to characterize proteases from a number of sources.

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Additional information

Three Letter Sequence

Isovaleryl-Val-Val-Sta-Ala-Sta

Molecular Weight

685.89

Molecular Formula

C34H63N5O9

Sequence

VVA

Solubility

Soluble to 1 mg/ml in ethanol with gentle warming

Appearance

Freeze dried solid

Storage

Store dry, dark and frozen

Purity

>98% by HPLC

Modifications

Val-1 =is N-terminal H-iso-Valeryl, Val-2 is Val-4-amino-3-hydroxy-6-methylheptanoyl, Alanine-3 is Ala-4-amino-3-hydroxy-6-methylheptanoic-acid

Searchable Words

26305-03-3, Pepstatin A, aspartyl peptidases, proteases, pepsin, renin, cathepsin D, bovine chymosin, and protease B, ?-secretase, retroviral proteases, PI-120, PI120