Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Calpain inhibitor.

PD 150606 is a cell-permeable non-peptide calpain inhibitor with Ki values for ν and m-calpains of 0.21 and 0.37 M. PD 150606 targets the calcium binding sites of calpain and possesses very high selectivity for calpains relative to other proteases, acting as a non-competitive inhibitor with regard to the substrate.

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