PD 150606
£85.00 10mg
Calpain inhibitor.
PD 150606 is a cell-permeable non-peptide calpain inhibitor with Ki values for ν and m-calpains of 0.21 and 0.37 M. PD 150606 targets the calcium binding sites of calpain and possesses very high selectivity for calpains relative to other proteases, acting as a non-competitive inhibitor with regard to the substrate.
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Additional information
| Three Letter Sequence | Z-3-4-Iodophenyl-2-mercapto-2-propenoic acid |
|---|---|
| Molecular Weight | 306.12 |
| Molecular Formula | C9H7IO2S |
| Sequence | Z-3-4-Iodophenyl-2-mercapto-2-propenoic acid |
| Solubility | Soluble in DMSO and ethanol |
| Appearance | Off white solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | ‰¥95% (HPLC) |