Parasin I
£145.00 1mg
Broad spectrum antimicrobial.
Parasin I is an amphipathic antimicrobial peptide derived from the N-terminus of histone H2A of the catfish Parasilurus asotus. Parasin I has a wide antimicrobial activity and is about 12-100 times more potent than magainin 2 against a wide spectrum of microorganisms, without any hemolytic activity. In response to epidermal injury the catfish secretes parasin I into the epithelial mucosal layer, suggesting that it produces parasin I from its histone H2A by a specific protease upon injury to protect against invasion by microorganisms.
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Additional information
| Three Letter Sequence | H-Lys-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Val-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-OH |
|---|---|
| Molecular Weight | 2000.4 |
| Molecular Formula | C82H154N34O24 |
| Sequence | KGRGKQGGKVRAKAKTRSS |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store dry, dark and frozen |
| Purity | >95% BY HPLC |
| Searchable Words | 219552-69-9, H-KGRGKQGGKVRAKAKTRSS-OH, KGRGKQGGKVRAKAKTRSS, Parasin I , amphipathic, antimicrobial peptide |