Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Broad spectrum antimicrobial.

Parasin I is an amphipathic antimicrobial peptide derived from the N-terminus of histone H2A of the catfish Parasilurus asotus. Parasin I has a wide antimicrobial activity and is about 12-100 times more potent than magainin 2 against a wide spectrum of microorganisms, without any hemolytic activity. In response to epidermal injury the catfish secretes parasin I into the epithelial mucosal layer, suggesting that it produces parasin I from its histone H2A by a specific protease upon injury to protect against invasion by microorganisms.

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