Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Quorum sensing peptide from the Bacillus cereus group.

PapRIV is a quorum sensing heptapeptide originating from the Bacillus cereus group, which comprises a number of highly related species. PapRIV possesses in vitro pro-inflammatory effects on microglial BV-2 cell lines and is able to cross the gastro-intestinal tract and the blood brain barrier. PapRIV shows very high brain influx, suggesting a role in gut-brain signalling.