P5091

£75.00 10mg

Ubiquitin specific protease 7 (USP7) inhibitor.

P5091 is a selective and inhibitor of ubiquitin-specific protease 7 (USP7) with an IC50 of 4.2 ?M. P5091 displays little or no inhibition of other USP variants or proteases such as caspase, cathepsins and serine proteases but does have some activity at USP47. P5091 induces elevated p53 and apoptosis in cancer cell lines and possesses antiangiogenic activity in vivo.

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SKU: PI-100 Categories: ,

Additional information

Three Letter Sequence

1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone

Molecular Weight

348.22

Molecular Formula

C12H7Cl2NO3S2

Sequence

1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone

Solubility

Soluble to 10 mM in DMSO

Appearance

Off-white solid

Storage

Store desiccated, frozen and in the dark

Purity

‰¥98% (HPLC)