P32/98
£85.00 10mg
Dipeptidyl peptidase IV (DPP IV) inhibitor.
P32/98, also known as isoleucyl thiazolidide, is a potent and selective cell permeable inhibitor of dipeptidyl peptidase IV (DPP IV) with a Ki of 130 nM. P32/98 inhibition of DPP IV prevents degradation of both gastric inhibitory peptide (GIP) and Glucagon-like peptide-1, enhancing insulin secretion. P32/98 improves glucose tolerance, insulin sensitivity and beta-cell glucose responsiveness in diabetic fatty rats following oral administration.
Please contact us for availability.
Additional information
| Other Names | Isoleucyl thiazolidide |
|---|---|
| Three Letter Sequence | (2S,3S)-2-Amino-3-methyl-1-(thiazolidin-3-yl)pentan-1-one hemifumarate |
| Molecular Weight | 260.35 |
| Molecular Formula | C9H18N2OS 1/2C4H4O4 |
| Sequence | (2S,3S)-2-Amino-3-methyl-1-(thiazolidin-3-yl)pentan-1-one hemifumarate |
| Solubility | Soluble in DMSO or in water (up to 20 mg/ml). |
| Appearance | White solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | 98% by TLC |