Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Endogenous neuromedin U receptor agonist.

Neuromedin S (human) is a 33-amino acid neuropeptide, originally isolated from rat brain as an endogenous ligand for two orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1, which have since been identified as the neuromedin U receptors NMU1 and NMU2. Neuromedin S (human) shares an identical C-terminal heptapeptide with human neuromedin U, but unlike human neuromedin U, which is widely distributed in the CNS and peripheral tissues, neuromedin S (human) mainly exists in the suprachiasmatic nucleus in the CNS. Neuromedin S (human) primarily regulates biological rhythms.

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