Myelin Basic Protein (85-99) Peptide Antagonist
£145.00 1mg
Candidate autoantigen in multiple sclerosis.
MBP (85-99) peptide antagonist, or J5, is a 15 amino acid peptide fragment designed on the binding motif of MBP 85-99 (myelin basic protein 85-99) to HLA-DR2 (human leukocyte antigen-DR2), which competes with and inhibits the binding of MBP (85-99) to HLA-DR2 and IL-2. MBP 85-99 is the the immunodominant epitope of MBP and a major candidate autoantigen in multiple sclerosis (MS), making this peptide a useful tool for MS research.
Please contact us for availability.
Additional information
| Three Letter Sequence | H-Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala-Ala-Ala-Ala-Pro-Ala-OH |
|---|---|
| Molecular Weight | 1543.8 |
| Molecular Formula | C70H114N18O21 |
| Sequence | EKPKVEAYKAAAAPA |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store frozen and desiccated in the dark |
| Purity | >95% by HPLC |
| Searchable Words | MBP (85-99) peptide antagonist, J5, myelin basic protein 85-99), HLA-DR2, human leukocyte antigen-DR2), epitope, MBP, autoantigen, multiple sclerosis, MS, 444305-16-2, H-EKPKVEAYKAAAAPA-OH, EKPKVEAYKAAAAPA, NR-120, NR120 |