Myelin Basic Protein (85-99) Peptide Antagonist

£145.00 1mg

Candidate autoantigen in multiple sclerosis.

MBP (85-99) peptide antagonist, or J5, is a 15 amino acid peptide fragment designed on the binding motif of MBP 85-99 (myelin basic protein 85-99) to HLA-DR2 (human leukocyte antigen-DR2), which competes with and inhibits the binding of MBP (85-99) to HLA-DR2 and IL-2. MBP 85-99 is the the immunodominant epitope of MBP and a major candidate autoantigen in multiple sclerosis (MS), making this peptide a useful tool for MS research.

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SKU: NR-120 Categories: ,

Additional information

Three Letter Sequence

H-Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala-Ala-Ala-Ala-Pro-Ala-OH

Molecular Weight

1543.8

Molecular Formula

C70H114N18O21

Sequence

EKPKVEAYKAAAAPA

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store frozen and desiccated in the dark

Purity

>95% by HPLC

Searchable Words

MBP (85-99) peptide antagonist, J5, myelin basic protein 85-99), HLA-DR2, human leukocyte antigen-DR2), epitope, MBP, autoantigen, multiple sclerosis, MS, 444305-16-2, H-EKPKVEAYKAAAAPA-OH, EKPKVEAYKAAAAPA, NR-120, NR120