Myelin Basic Protein (85-99) peptide antagonist
£145.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Candidate autoantigen in multiple sclerosis.
MBP (85-99) peptide antagonist, or J5, is a 15 amino acid peptide fragment designed on the binding motif of MBP 85-99 (myelin basic protein 85-99) to HLA-DR2 (human leukocyte antigen-DR2), which competes with and inhibits the binding of MBP (85-99) to HLA-DR2 and IL-2. MBP 85-99 is the the immunodominant epitope of MBP and a major candidate autoantigen in multiple sclerosis (MS), making this peptide a useful tool for MS research.
Please contact us for availability.
Additional information
| Three Letter Sequence | H-Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala-Ala-Ala-Ala-Pro-Ala-OH |
|---|---|
| Molecular Weight | 1543.8 |
| Molecular Formula | C70H114N18O21 |
| Sequence | EKPKVEAYKAAAAPA |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store frozen and desiccated in the dark |
| Purity | >95% by HPLC |
| Searchable Words | MBP (85-99) peptide antagonist, J5, myelin basic protein 85-99), HLA-DR2, human leukocyte antigen-DR2), epitope, MBP, autoantigen, multiple sclerosis, MS, 444305-16-2, H-EKPKVEAYKAAAAPA-OH, EKPKVEAYKAAAAPA, NR-120, NR120 |