Magainin 2

£95.00 1mg

Broad spectrum antimicrobial.

Magainins are closely related 23 amino acid amphipathic cationic peptides with broad-spectrum antimicrobial activities, originally extracted from the skin of the African clawed frog Xenopus laevis. Magainins 1 and magainin 2 are closely related hemolytic peptides which inhibit growth of bacteria by permeabilizing the cell membranes without significant toxicity against mammalian cells. The main target of magainin 1 and 2 is thought to be the lipid matrix of the membranes. Both magainin 1 and 2 are also cytotoxic to cancer cells and exhibit inhibitory action toward herpes simplex virus 1 and 2.

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SKU: AM-101 Categories: ,

Additional information

Other Names

Maganin-2 , Mag-2

Three Letter Sequence

H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH

Molecular Weight

2466.9

Molecular Formula

C114H180N30O29S

Sequence

GIGKFLHSAKKFGKAFVGEIMNS

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

H-GIGKFLHSAKKFGKAFVGEIMNS-OH, GIGKFLHSAKKFGKAFVGEIMNS, 108433-95-0, Magainin 2, antimicrobial, African clawed frog Xenopus laevis, hemolytic, haemolytic, permeabilizing the cell membranes, cytotoxic, cancer, herpes simplex virus, AM-101, AM101, Maganin-2, Mag-2