IRBP (651-670) (Human)
£175.00 1mg
Residues 651 to 670 of human interphotoreceptor retinoid binding protein (IRBP).
IRBP (651-670) (human), sometimes referred to as hIRBP651-670 or human IRBP651-670, is amino acid residues 651 to 670 of human interphotoreceptor retinoid binding protein (IRBP), which has been identified as a new uveitogenic epitope. IRBP (651-670) (human) is uveitogenic for mice of the H-2b haplotype and elicits experimental autoimmune uveitis (EAU) with a higher severity and incidence in C57BL/6 mice than the previously characterized IRBP (1-20) (human) epitope. Co-immunization with IRBP (1-20) (human) and IRBP (651-670) human is additive but not synergistic. IRBP (651-670) (human) appears to be an epitope naturally processed from a conserved region of native IRBP.
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Additional information
| Other Names | hIRBP651-670, human IRBP651-670 |
|---|---|
| Three Letter Sequence | H-Leu-Ala-Gln-Gly-Ala-Tyr-Arg-Thr-Ala-Val-Asp-Leu-Glu-Ser-Leu-Ala-Ser-Gln-Leu-Thr-OH |
| Molecular Weight | 2107.35 |
| Molecular Formula | C91H151N25O32 |
| Sequence | LAQGAYRTAVDLESLASQLT |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | IRBP (651-670) (human), hIRBP651-670, human IRBP651-670, epitope, immunology, human interphotoreceptor retinoid binding protein, IRBP, uveitogenic, experimental autoimmune uveitis, EAU, H-LAQGAYRTAVDLESLASQLT-OH, LAQGAYRTAVDLESLASQLT, IM-050, IM050 |