H10, Biotinylated

£145.00 1mg

SKU: PP-010 Categories: ,

Biotinylated version of anterior gradient 2 (AGR2) binding peptide H10.

H10, biotinylated is the N-terminal biotinylated version of the anterior gradient 2 (AGR2) binding peptide H10 (MKMQVRIYLV) which was identified by mRNA display from a complex (>1011) library. AGR2 is a cancer-associated protein and increased levels of extracellular AGR2 (eAGR2) have been correlated with poor prognosis in cancer patients, making it a potential biomarker. H10 possesses high affinity binding to AGR2 with a KD of 6.4 nM, and has been used as the capture reagent in an AGR2 ELISA. H10 can also inhibit cancer cell migration in breast and prostate cancer cell lines.

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Additional information

Three Letter Sequence

Biotin-Gly-Gly-Gly-Ser-Gly-Met-Lys-Met-Gln-Val-Arg-Ile-Tyr-Leu-Val-OH

Molecular Weight

1822.26

Molecular Formula

C79H132N22O21S3

Sequence

Biotin-GGGSGMKMQVRIYLV

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

Biotinylated at N terminus

Searchable Words

H10, biotinylated, Biotin-GGGSGMKMQVRIYLV-OH, GGGSGMKMQVRIYLV, PP-010