[Des-octanoyl]-Ghrelin (Human)

£125.00 1mg

Non acylated form of ghrelin.

[Des-octanoyl]-Ghrelin (human) is the more stable, non-acylated and major circulating isoform of ghrelin (human ), with a half-life of 35 min in plasma compared with 10 minutes for acylated ghrelin. Unlike ghrelin, [des-octanoyl]-ghrelin (human) does not bind to the ghrelin receptor (GHS-R1a), or induce growth hormone release. [Des-octanoyl]-ghrelin (human) exerts negative inotropic effects in papillary muscle and displays cardioprotective activity, inhibits cell proliferation in breast and prostate cancer cell lines and promotes adipogenesis in vivo.

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SKU: GR-010 Categories: ,

Additional information

Other Names

Des-acyl ghrelin, Unacylated ghrelin, UAG

Three Letter Sequence

H-Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH

Molecular Weight

3244.51

Molecular Formula

C141H235N47O41

Sequence

GSSFLSPEHQRVQQRKESKKPPAKLQPR

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

[Des-octanoyl]-Ghrelin (human), 313951-59-6, GSSFLSPEHQRVQQRKESKKPPAKLQPR, des-acyl ghrelin