CGRP (8-37) (rat)

£175.00 1mg

SKU: CG-020 Categories: , ,

Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

CGRP antagonist.

CGRP (8-37) (rat) is a truncated version of calcitonin gene-related peptide (CGRP) that binds to the CGRP receptor with similar affinity and acts as a competitive and highly selective CGRP1 receptor antagonist. CGRP (8-37) (rat) possesses hypothermic and antinociceptive effects and can abolish mechanical and thermal allodynia in chronic central neuropathic pain models.

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Additional information

Other Names

CGRP 8-37 (rat), Calcitonin Gene-Related Peptide 8-37 (rat), ?-CGRP (8-37)

Three Letter Sequence

H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2

Molecular Weight

3127.55

Molecular Formula

C138H224N42O41

Sequence

VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

C-terminal amide

Searchable Words

CGRP 8-37 (rat), VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2, VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF, 129121-73-9