CGRP (8-37) (Rat)

£175.00 1mg

SKU: CG-020 Categories: , ,

CGRP antagonist.

CGRP (8-37) (rat) is a truncated version of calcitonin gene-related peptide (CGRP) that binds to the CGRP receptor with similar affinity and acts as a competitive and highly selective CGRP1 receptor antagonist. CGRP (8-37) (rat) possesses hypothermic and antinociceptive effects and can abolish mechanical and thermal allodynia in chronic central neuropathic pain models.

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Additional information

Other Names

CGRP 8-37 (rat), Calcitonin Gene-Related Peptide 8-37 (rat), ?-CGRP (8-37)

Three Letter Sequence

H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2

Molecular Weight

3127.55

Molecular Formula

C138H224N42O41

Sequence

VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

C-terminal amide

Searchable Words

CGRP 8-37 (rat), VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2, VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF, 129121-73-9