Camostat Mesylate

£35.00 10mg

Serine protease inhibitor.

Camostat is an orally active serine protease inhibitor which can inhibit plasmin, kallikrein, thrombin and trypsin, and attenuate pancreatic fibrosis in vivo. Camostat also inhibits influenza virus replication in human tracheal epithelial cells and reduces infection of Calu-3 lung cells by SARS-CoV-2 through inhibition of the serine protease TMPRSS2, required for viral spike protein priming. In mice, camostat was effective in protecting against death following a lethal SARS-CoV infection, with a survival rate of 60%.

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SKU: CV-001 Categories: ,

Additional information

Three Letter Sequence

4-2-2-dimethylamino-2-oxoethoxy-2-oxoethylphenyl 4-guanidinobenzoate, methanesulfonic acid salt

Molecular Weight

494.5

Molecular Formula

C20H22N4O5 CH3SO3H

Sequence

4-2-2-dimethylamino-2-oxoethoxy-2-oxoethylphenyl 4-guanidinobenzoate, methanesulfonic acid salt

Solubility

Soluble in water and DMSO to 50mg/ml

Appearance

Off-white powder

Storage

Store desiccated, frozen and in the dark

Purity

>98% by HPLC