Bid BH3?

£95.00 1mg

Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Fragment of the BH3 domain of BID.

Bid BH3 peptide is a fragment derived from the BH3 domain of the pro-apoptotic protein Bid (BH3-interacting domain death agonist). Bid is a member of the BH3-only subset of the BCL-2 family of proteins that are critical control points in apoptosis and Bid is the first of the BH3 subset reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax and the BH3 peptide domain, excised from the entire BH3-only molecule, can function as a specific death ligand itself.

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Additional information

Other Names

Bid BH3 peptide, BIDBH3

Three Letter Sequence

H-Glu-Asp-Ile-Ile-Arg-Asn-Ile-Ala-Arg-His-Leu-Ala-Gln-Val-Gly-Asp-Ser-Met-Asp-Arg-OH

Molecular Weight

2309.59

Molecular Formula

C95H161N3 O32S

Sequence

EDIIRNIARHLAQVGDSMDR

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

Bid BH3 Peptide, EDIIRNIARHLAQVGDSMDR, PP-080