AMPR-22
£145.00 1mg
AMPR-22 is an optimised antimicrobial peptide derived from reactive oxygen species modulator 1 (Romo1), a mitochondrial protein encoded by the nucleus which is a nonselective cation channel in the mitochondrial inner membrane. AMPR-22 shows broad-spectrum antimicrobial activity against 17 sepsis causing bacteria, including multidrug resistant (MDR) strains, by inducing membrane permeabilization. In vivo, AMPR-22 enables a remarkable survival rate in mice injected with MDR bacteria in murine models of sepsis.
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Additional information
| Three Letter Sequence | H-Lys-Lys-Met-Met-Lys-Lys-Gly-Gly-Lys-Phe-Gly-Thr-Phe-Met-Ala-Ile-Gly-Gly-Ile-Arg-OH |
|---|---|
| Molecular Weight | 2186.78 |
| Molecular Formula | 2186.78 |
| Sequence | KKMMKKGGKFGTFMAIGGIR |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | AMPR-22, antimicrobial peptide derived from Romo1, AM-330, KKMMKKGGKFGTFMAIGGIR |