AMPR-22

£145.00 1mg

AMPR-22 is an optimised antimicrobial peptide derived from reactive oxygen species modulator 1 (Romo1), a mitochondrial protein encoded by the nucleus which is a nonselective cation channel in the mitochondrial inner membrane. AMPR-22 shows broad-spectrum antimicrobial activity against 17 sepsis causing bacteria, including multidrug resistant (MDR) strains, by inducing membrane permeabilization. In vivo, AMPR-22 enables a remarkable survival rate in mice injected with MDR bacteria in murine models of sepsis.

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SKU: AM-330 Categories: ,

Additional information

Three Letter Sequence

H-Lys-Lys-Met-Met-Lys-Lys-Gly-Gly-Lys-Phe-Gly-Thr-Phe-Met-Ala-Ile-Gly-Gly-Ile-Arg-OH

Molecular Weight

2186.78

Molecular Formula

2186.78

Sequence

KKMMKKGGKFGTFMAIGGIR

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

AMPR-22, antimicrobial peptide derived from Romo1, AM-330, KKMMKKGGKFGTFMAIGGIR