alpha-MSH
£125.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Endogenous melanocortin receptor agonist.
alpha-MSH is an endogenous melanocortin receptor agonist with Ki values of 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively. alpha-MSH is primarily a pigmentary hormone of the vertebrates and reduces the concentration of proinflammatory mediators through the induction of cyclic adenosine monophosphate (cAMP), controlling inflammation in the brain and peripheral organs. alpha-MSH also possesses antimicrobial properties.
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Additional information
| Other Names | a-Melanotropin, a-N-acetyl-ACTH(1-13)-NH2, alpha-melanocyte-stimulating hormone |
|---|---|
| Three Letter Sequence | AcSer-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 |
| Molecular Weight | 1664.88 |
| Molecular Formula | C77H109N21O19S |
| Sequence | AcSYSMEHFRWGKPV-NH2 |
| Solubility | Soluble to 0.60 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | N terminal acetyl, C terminal amide |
| Searchable Words | ?-MSH, a-Melanotropin, a-N-acetyl-ACTH(1-13)-NH2, SYSMEHFRWGKPV, 581-05-5, MC-010 |