alpha-MSH
£125.00 1mg
Endogenous melanocortin receptor agonist.
alpha-MSH is an endogenous melanocortin receptor agonist with Ki values of 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively. alpha-MSH is primarily a pigmentary hormone of the vertebrates and reduces the concentration of proinflammatory mediators through the induction of cyclic adenosine monophosphate (cAMP), controlling inflammation in the brain and peripheral organs. alpha-MSH also possesses antimicrobial properties.
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Additional information
| Other Names | a-Melanotropin, a-N-acetyl-ACTH(1-13)-NH2, alpha-melanocyte-stimulating hormone |
|---|---|
| Three Letter Sequence | AcSer-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 |
| Molecular Weight | 1664.88 |
| Molecular Formula | C77H109N21O19S |
| Sequence | AcSYSMEHFRWGKPV-NH2 |
| Solubility | Soluble to 0.60 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | N terminal acetyl, C terminal amide |
| Searchable Words | ?-MSH, a-Melanotropin, a-N-acetyl-ACTH(1-13)-NH2, SYSMEHFRWGKPV, 581-05-5, MC-010 |