alpha-MSH

£125.00 1mg

Endogenous melanocortin receptor agonist.

alpha-MSH is an endogenous melanocortin receptor agonist with Ki values of 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively. alpha-MSH is primarily a pigmentary hormone of the vertebrates and reduces the concentration of proinflammatory mediators through the induction of cyclic adenosine monophosphate (cAMP), controlling inflammation in the brain and peripheral organs. alpha-MSH also possesses antimicrobial properties.

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SKU: MC-010 Categories: ,

Additional information

Other Names

a-Melanotropin, a-N-acetyl-ACTH(1-13)-NH2, alpha-melanocyte-stimulating hormone

Three Letter Sequence

AcSer-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

Molecular Weight

1664.88

Molecular Formula

C77H109N21O19S

Sequence

AcSYSMEHFRWGKPV-NH2

Solubility

Soluble to 0.60 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

N terminal acetyl, C terminal amide

Searchable Words

?-MSH, a-Melanotropin, a-N-acetyl-ACTH(1-13)-NH2, SYSMEHFRWGKPV, 581-05-5, MC-010