Nitazoxanide
£55.00 10mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Broad spectrum antiparasitic and antiviral.
Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used clinically in the treatment of various helminthic, protozoal, and viral infections. The anti-protozoal activity of nitazoxanide is due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction required for anaerobic energy metabolism. As an antiviral agent nitazoxanide is active against many RNA and DNA viruses including influenza, hepatitis B and C, RSV and dengue and shows inhibitory efficacy against the coronavirus protease in vitro.
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Additional information
Other Names | NTZ |
---|---|
Three Letter Sequence | O-[N-(5-Nitrothiazol-2-yl)carbamoyl]phenyl acetate |
Molecular Weight | 307.3 |
Molecular Formula | C12H9N3O5S |
Sequence | O-[N-(5-Nitrothiazol-2-yl)carbamoyl]phenyl acetate |
Solubility | Soluble in DMSO to 50mg/ml |
Appearance | Off-white powder |
Storage | Store desiccated, frozen and in the dark |
Purity | >98% by hplc, NMR conforms to standard |