Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Serine protease inhibitor.

Nafamostat mesylate is a serine protease inhibitor. It inhibits a large number of Lys/Arg specific serine proteinases, and is also a tryptase inhibitor. In vivo nafamostat is a fast-acting proteolytic inhibitor and used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. Nafamostat also has some antiviral and anti-cancer properties and has been identified as a potential treatment for COVID-19.

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