Pepstatin A
£65.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Aspartyl peptidase inhibitor.
Pepstatin A is an inhibitor of aspartyl peptidases. Pepstatin A is highly selective for proteases such as pepsin, renin, cathepsin D, bovine chymosin, and protease B and does not inhibit thiol proteases, neutral proteases, or serine proteases. Pepstatin A also inhibits solubilized ?-secretase and retroviral proteases and has been used to characterize proteases from a number of sources.
Please contact us for availability.
Additional information
| Three Letter Sequence | Isovaleryl-Val-Val-Sta-Ala-Sta |
|---|---|
| Molecular Weight | 685.89 |
| Molecular Formula | C34H63N5O9 |
| Sequence | VVA |
| Solubility | Soluble to 1 mg/ml in ethanol with gentle warming |
| Appearance | Freeze dried solid |
| Storage | Store dry, dark and frozen |
| Purity | >98% by HPLC |
| Modifications | Val-1 =is N-terminal H-iso-Valeryl, Val-2 is Val-4-amino-3-hydroxy-6-methylheptanoyl, Alanine-3 is Ala-4-amino-3-hydroxy-6-methylheptanoic-acid |
| Searchable Words | 26305-03-3, Pepstatin A, aspartyl peptidases, proteases, pepsin, renin, cathepsin D, bovine chymosin, and protease B, ?-secretase, retroviral proteases, PI-120, PI120 |