IRBP (651-670) (human)
£175.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Residues 651 to 670 of human interphotoreceptor retinoid binding protein (IRBP).
IRBP (651-670) (human), sometimes referred to as hIRBP651-670 or human IRBP651-670, is amino acid residues 651 to 670 of human interphotoreceptor retinoid binding protein (IRBP), which has been identified as a new uveitogenic epitope. IRBP (651-670) (human) is uveitogenic for mice of the H-2b haplotype and elicits experimental autoimmune uveitis (EAU) with a higher severity and incidence in C57BL/6 mice than the previously characterized IRBP (1-20) (human) epitope. Co-immunization with IRBP (1-20) (human) and IRBP (651-670) human is additive but not synergistic. IRBP (651-670) (human) appears to be an epitope naturally processed from a conserved region of native IRBP.
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Additional information
| Other Names | hIRBP651-670, human IRBP651-670 |
|---|---|
| Three Letter Sequence | H-Leu-Ala-Gln-Gly-Ala-Tyr-Arg-Thr-Ala-Val-Asp-Leu-Glu-Ser-Leu-Ala-Ser-Gln-Leu-Thr-OH |
| Molecular Weight | 2107.35 |
| Molecular Formula | C91H151N25O32 |
| Sequence | LAQGAYRTAVDLESLASQLT |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | IRBP (651-670) (human), hIRBP651-670, human IRBP651-670, epitope, immunology, human interphotoreceptor retinoid binding protein, IRBP, uveitogenic, experimental autoimmune uveitis, EAU, H-LAQGAYRTAVDLESLASQLT-OH, LAQGAYRTAVDLESLASQLT, IM-050, IM050 |