A20FMDV2
£125.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Selective alpha-v beta-6 (v6) integrin antagonist.
A20FMDV2 is a peptide derived from the foot-and-mouth disease virus with a high affinity and selectivity for the alpha-v beta-6 (v6) arginyl-glycinyl-aspartic acid (RGD)-binding integrin, inhibiting alphavbeta6-ligand binding with a IC50 of 3 nmol/L, an activity 1,000-fold more selective for alphavbeta6 than for other RGD-directed integrins (alphavbeta3, alphavbeta5, and alpha5beta1).
Additional information
| Three Letter Sequence | H-Asn-Ala-Val-Pro-Asn-Leu-Arg-Gly-Asp-Leu-Gln-Val-Leu-Ala-Gln-Lys-Val-Ala-Arg-Thr-NH2 |
|---|---|
| Molecular Weight | 2162.5 |
| Molecular Formula | C93H164N32O27 |
| Sequence | NAVPNLRGDLQVLAQKVART-NH2 |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | We recommend storage desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | A20FMDV2, 932699-03-1, H-NAVPNLRGDLQVLAQKVART-NH2, NAVPNLRGDLQVLAQKVART, foot-and-mouth, alpha-v beta-6, ?v?6, arginyl-glycinyl-aspartic acid, IG-010, IG010 |