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[Leu144, Arg147]-PLP (139-151)

[Leu144, Arg147]-PLP (139-151)

£75.00 1mg

SKU: NR-040 Categories: , ,

Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

T cell receptor antagonist.

[Leu144, Arg147]-PLP (139-151) is an analogue of PLP (139-151) which can act as a T-cell receptor antagonist, able to prevent development of the autoimmune disease model experimental allergic encephalomyelitis (EAE). [Leu144, Arg147]-PLP (139-151 prevents EAE when co-administered with native PLP(139-151) and can limit progression of EAE if given early after the onset of disease in mice.

Please contact us for availability.

Additional information

Three Letter Sequence

H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH
Molecular Weight

1467.7
Molecular Formula

C67H110N20O17
Sequence

HSLGKLLGRPDKF
Solubility

Soluble in dilute acid
Appearance

Freeze dried solid
Storage

Store desiccated, frozen and in the dark
Purity

>95% by HPLC
Searchable Words

[Leu144, Arg147]-PLP (139-151), 188859-65-6, T-cell receptor antagonist, autoimmune disease model experimental allergic encephalomyelitis, EAE, H-HSLGKLLGRPDKF-OH, HSLGKLLGRPDKF, NR-040, NR040