WRW4
£75.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Selective formyl peptide receptor 2 (FPR2) antagonist.
WRW4 is a selective antagonist of formyl peptide receptor 2 (FPR2) signalling, which can inhibit WKYMVm binding to FPR2 with an C50 of 0.23 μM and can also inhibit intracellular calcium release induced by WKYMVm, MMK 1, amyloid 42, and F peptide. WRW4 inhibits FPR2-mediated signalling in human neutrophils and blocks chemotactic migration and superoxide generation by amyloid 42 peptide. WRW4 can reduce Brucella proliferation in animal models.
Please contact us for availability.
Additional information
| Three Letter Sequence | H-Trp-Arg-Trp-Trp-Trp-Trp-NH2 |
|---|---|
| Molecular Weight | 1104.28 |
| Molecular Formula | C61H65N15O6 |
| Sequence | WRWWWW-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C-terminal amide |
| Searchable Words | WRW4, 878557-55-2, WRWWWW-NH2, FR-020 |