tcY-NH2

£125.00 1mg

Selective PAR4 antagonist.

tcY-NH2 is a selective PAR4 antagonist peptide which can block platelet aggregation caused by thrombin, without affecting ADP mediated aggregation. tcY-NH-2 also blocks PAR4 activation of the ERK pathway and through this mechanism can mediate aortic vascular smooth muscle cell migration and proliferation in rat models.

SKU: PR-050 Categories: ,

Additional information

Other Names

(trans-Cinnamoyl)-YPGKF-NH2, trans-cinnamoyl-YPGKF-NH2

Three Letter Sequence

trans-Cinnamoyl-Tyr-Pro-Gly-Lys-Phe-N2

Molecular Weight

739.87

Molecular Formula

C40H49N7O7

Sequence

trans-Cinnamoyl-YPGKF-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

Tyr-1 = trans-Cinnamoyl-Tyr, Phe-5 = C-terminal amide

Searchable Words

tcY-NH2, (trans-Cinnamoyl)-YPGKF-NH2, 327177-34-4, trans-Cinnamoyl-YPGKF-NH2