Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Cell penetrating cationic peptide derived from the N-terminus of the Tat protein.

Tat (48 – 60), also known as HIV-1 Tat (48 – 60), is a cell penetrating cationic peptide derived from the N-terminus of the Tat protein, which is a transactivator of the transcription protein present in the human immunodeficiency virus (HIV). Tat (48-60) is an arginine-rich basic peptide which has three domains that function to aid HIV through transactivation, DNA binding and nuclear transport. Tat (48-60) posseses antibacterial activity but is mainly used for the non disruptive transport of exogenous macromolecules into cells.

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