Spexin

£75.00 1mg

Endogenous galanin receptor 2/3 agonist.

Spexin, or neuropeptide Q, is an endogenous galanin receptor 2/3 agonist with EC50 values of 45 and 112 nM respectively, and no significant activity at galanin receptor 1. Spexin is a satiety inducing peptide which inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet induced obese mice and rats. ? Spexin gene expression is markedly down regulated in obese human fat. Spexin also posseses anxiolytic properties.

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SKU: GA-010 Categories: ,

Additional information

Other Names

Neuropeptide Q, NPQ, Spexin (36 – 49) amidated

Three Letter Sequence

Asn-Trp-Thr-Pro-Gln-Ala-Met-Leu-Tyr-Leu-Lys-Gly-Ala-Gln-NH2

Molecular Weight

1619.9

Molecular Formula

C74H114N20O19S

Sequence

NWTPQAMLYLKGAQ-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

C terminal amide

Searchable Words

Spexin, Neuropeptide Q, NPQ, Spexin-1, Spexin (36 – 49) amidated, 1370290-58-6