Spexin
£75.00 1mg
Endogenous galanin receptor 2/3 agonist.
Spexin, or neuropeptide Q, is an endogenous galanin receptor 2/3 agonist with EC50 values of 45 and 112 nM respectively, and no significant activity at galanin receptor 1. Spexin is a satiety inducing peptide which inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet induced obese mice and rats. ? Spexin gene expression is markedly down regulated in obese human fat. Spexin also posseses anxiolytic properties.
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Additional information
| Other Names | Neuropeptide Q, NPQ, Spexin (36 – 49) amidated |
|---|---|
| Three Letter Sequence | Asn-Trp-Thr-Pro-Gln-Ala-Met-Leu-Tyr-Leu-Lys-Gly-Ala-Gln-NH2 |
| Molecular Weight | 1619.9 |
| Molecular Formula | C74H114N20O19S |
| Sequence | NWTPQAMLYLKGAQ-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | Spexin, Neuropeptide Q, NPQ, Spexin-1, Spexin (36 – 49) amidated, 1370290-58-6 |