SOR-C13

£125.00 1mg

TRPV6 antagonist.

SOR-C13 is a carboxy terminal truncated peptide derived from the 54 residue paralytic peptide soricidin, found in the paralytic venom of the short-tailed shrew Blarina brevicauda. SOR-C13 is a high affinity, use dependent antagonist of human transient receptor potential vanilloid 6 (TRPV6) channels with an IC50 of 14 nM. TRPV6 is a non-voltage gated calcium channel implicated in malignancies and poor prognosis in breast cancer. In vivo, SOR-C13 reduces the growth of human ovarian xenografts in NOD/SCID mouse models.

Please contact us for availability.

SKU: TP-020 Categories: ,

Additional information

Three Letter Sequence

H-Lys-Glu-Phe-Leu-His-Pro-Ser-Lys-Val-Asp-Leu-Pro-Arg-OH

Molecular Weight

1565.81

Molecular Formula

C72H116N20O19

Sequence

KEFLHPSKVDLPR

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

SOR-C13, TP-020, 1187852-48-7, KEFLHPSKVDLPR