Somatostatin 14

£75.00 1mg

SKU: SS-010 Categories: , ,

Endogenous somatostatin receptor agonist.

Somatostatin, also known as growth hormone inhibiting hormone, is an endogenous peptide hormone. Somatostatin has two active forms produced by the alternative cleavage of a single preproprotein, one consisting of 14 amino acids, the other consisting of 28 amino acids. Somatostin 14 is the shorter isoform and works primarily in the brain, while the 28 amino acid form acts in the GI tract. Somatostatin 14 regulates the endocrine system and affects neurotransmission and cell proliferation though interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.

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Additional information

Other Names

Somatostatin; Growth hormone inhibiting hormone, SRIF 14

Three Letter Sequence

H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (disulfide bridge between cysteine 3 and cysteine 14)

Molecular Weight

1637.88

Molecular Formula

C76H104N18O19S2

Sequence

AGCKNFFWKTFTSC

Solubility

Soluble to 0.30 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

Disulfide bridge between cysteine 3 and cysteine 14

Searchable Words

Somatostatin, 51110-01-1, AGCKNFFWKTFTSC , Somatostatin-14; Growth hormone inhibiting hormone, SRIF 14