SHBG141-161
£135.00 1mg
GPRC6A agonist.
SHBG141-161 is a peptide corresponding to amino acids 141-161 of sex hormone binding globulin (SHBG), the loop region of SHBG connecting ?-strands 11 and 12. SHBG141-161 is an agonist of the class C orphan G protein coupled receptor GPRC6A, a major regulator of energy metabolism and male fertility, and SHBG141-161 competes for binding to it with its endogenous ligand undercarboxylated osteocalcin (ucOCN). In vitro, SHBG141-161 stimulates insulin secretion from ?-cells and also the production and release of testosterone from Leydig and Langerhans ?-cells cell lines.
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Additional information
| Other Names | SHBG(141 “161) domain peptide, SHBG(141 “161) |
|---|---|
| Three Letter Sequence | H-Ile-Ala-Leu-Gly-Gly-Leu-Leu-Phe-Pro-Ala-Ser-Asn-Leu-Arg-Leu-Pro-Leu-Val-Pro-Ala-Leu-OH |
| Molecular Weight | 2145.66 |
| Molecular Formula | C103H173N25O24 |
| Sequence | IALGGLLFPASNLRLPLVPAL |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | OR-030, OR030, SHBG141 “161, IALGGLLFPASNLRLPLVPAL, |