SHBG141-161

£135.00 1mg

GPRC6A agonist.

SHBG141-161 is a peptide corresponding to amino acids 141-161 of sex hormone binding globulin (SHBG), the loop region of SHBG connecting ?-strands 11 and 12. SHBG141-161 is an agonist of the class C orphan G protein coupled receptor GPRC6A, a major regulator of energy metabolism and male fertility, and SHBG141-161 competes for binding to it with its endogenous ligand undercarboxylated osteocalcin (ucOCN). In vitro, SHBG141-161 stimulates insulin secretion from ?-cells and also the production and release of testosterone from Leydig and Langerhans ?-cells cell lines.

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SKU: OR-030 Categories: ,

Additional information

Other Names

SHBG(141 “161) domain peptide, SHBG(141 “161)

Three Letter Sequence

H-Ile-Ala-Leu-Gly-Gly-Leu-Leu-Phe-Pro-Ala-Ser-Asn-Leu-Arg-Leu-Pro-Leu-Val-Pro-Ala-Leu-OH

Molecular Weight

2145.66

Molecular Formula

C103H173N25O24

Sequence

IALGGLLFPASNLRLPLVPAL

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

OR-030, OR030, SHBG141 “161, IALGGLLFPASNLRLPLVPAL,