SBP1
£95.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Binds to the SARS-CoV-2 receptor binding domain.
SBP1 is a 23 amino acid fragment of the angiotensin-converting enzyme 2 (ACE2) peptidase domain (PD) 1 helix, a key domain for the interaction of ACE2 with the severe acute respiratory syndrome coronavirus receptor binding domain (SARS-CoV-2-RBD). SBP1 binds to the SARS-CoV-2-RBD with an affinity comparable with the corresponding spike protein of SARS-CoV, and can potentially block the mechanism by which SARS-CoV-2 enters into cells. SBP1 offers an opportunity for therapeutic intervention in COVID-19.
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Additional information
| Three Letter Sequence | H-Ile-Glu-Glu-Gln-Ala-Lys-Thr-Phe-Leu-Asp-Lys-Phe-Asn-His-Glu-Ala-Glu-Asp-Leu-Phe-Tyr-Gln-Ser-NH2 |
|---|---|
| Molecular Weight | 2802.05 |
| Molecular Formula | C127H185N31O41 |
| Sequence | IEEQAKTFLDKFNHEAEDLFYQS-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | H-IEEQAKTFLDKFNHEAEDLFYQS-NH2, IEEQAKTFLDKFNHEAEDLFYQS-NH2, SBP1, angiotensin-converting enzyme 2, ACE2, severe acute respiratory syndrome coronavirus, SARS-CoV-2, spike protein, SARS-CoV, COVID-19, CV-050, CV050 |