SBP1

£95.00 1mg

Binds to the SARS-CoV-2 receptor binding domain.

SBP1 is a 23 amino acid fragment of the angiotensin-converting enzyme 2 (ACE2) peptidase domain (PD) 1 helix, a key domain for the interaction of ACE2 with the severe acute respiratory syndrome coronavirus receptor binding domain (SARS-CoV-2-RBD). SBP1 binds to the SARS-CoV-2-RBD with an affinity comparable with the corresponding spike protein of SARS-CoV, and can potentially block the mechanism by which SARS-CoV-2 enters into cells. SBP1 offers an opportunity for therapeutic intervention in COVID-19.

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SKU: CV-050 Categories: ,

Additional information

Three Letter Sequence

H-Ile-Glu-Glu-Gln-Ala-Lys-Thr-Phe-Leu-Asp-Lys-Phe-Asn-His-Glu-Ala-Glu-Asp-Leu-Phe-Tyr-Gln-Ser-NH2

Molecular Weight

2802.05

Molecular Formula

C127H185N31O41

Sequence

IEEQAKTFLDKFNHEAEDLFYQS-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Modifications

C terminal amide

Searchable Words

H-IEEQAKTFLDKFNHEAEDLFYQS-NH2, IEEQAKTFLDKFNHEAEDLFYQS-NH2, SBP1, angiotensin-converting enzyme 2, ACE2, severe acute respiratory syndrome coronavirus, SARS-CoV-2, spike protein, SARS-CoV, COVID-19, CV-050, CV050