Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Scrambled control peptide for rytvela.

Rytvela scrambled peptide, verytla, is a scrambled control for use in conjunction with rytvela, the all D peptide derived from an extracellular loop region of the interleukin-1 receptor accessory protein (IL-1RAcP), which acts as an allosteric negative modulator of the interleukin-1 receptor (IL-1R). In vivo rytvela is active in models of hyperthermia, inflammatory bowel disease and topically in contact dermatitis. Under these conditions rytvela scrambled peptide has no activity and is thus useful as a control.

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