Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Integrin receptor inhibitor.

RGDS peptide is a tetrapeptide found on fibronectin, fibrinogen, and von Willebrand factor, but not vitronectin or collagen. RGDS interacts with 51 and V3 integrins and interferes with the attachment of cells to fibronectin coated surfaces and also blocks the attachment of pathogens to cells. The interaction of RGDS peptide with cell surface integrins alters intracellular signalling in a cell and stimulus specific manner.

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