R18

£115.00 1mg

4.3.3 proteins antagonist.

R18, also known as R18 peptide is an antagonist of 14.3.3 proteins, a family of conserved regulatory molecules that have the ability to bind a multitude of functionally diverse signalling proteins, with a KD of approximately 80 nM. R18 competitively inhibits 14.3.3 ligand interactions without requiring phosphorylation and can block the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S.

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SKU: KS-120 Categories: ,

Additional information

Other Names

R18 peptide

Three Letter Sequence

H-Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro-OH

Molecular Weight

2309.6

Molecular Formula

C101H157N27O29S3

Sequence

PHCVPRDLSWLDLEANMCLP

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store frozen and desiccated in the dark

Purity

>95% by HPLC

Searchable Words

211364-78-2, H-PHCVPRDLSWLDLEANMCLP-OH, PHCVPRDLSWLDLEANMCLP, R18, R18 peptide, 14.3.3 proteins, KS-120, KS120