R 715

£145.00 1mg

Bradykinin B1 receptor antagonist.

R 715 is a potent and selective bradykinin B1 receptor antagonist with a pA2 of 8.49 and no activity at B2 receptors. R 715 is metabolically stable and can reduce mechanical hypernociception in a mouse model of neuropathic pain.

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SKU: PN-070 Categories: ,

Additional information

Three Letter Sequence

Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D?Nal-Ile-OH

Molecular Weight

1140,4

Molecular Formula

C57H81N13O12

Sequence

KRPPGFSXI

Solubility

Soluble to 5 mg/ml in water

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Modifications

Lys-1 is N-terminal Acetyl, X is D?Nal

Searchable Words

R 715, bradykinin B1, antagonist, hypernociception, neuropathy, pain, Ac-KRPPGFS-D?Nal-I-OH, Ac-KRPPGFS-D?Nal-I-OH, 185052-09-9, KRPPGFSXI, R715, PN-070, PN070