R 715
£145.00 1mg
Bradykinin B1 receptor antagonist.
R 715 is a potent and selective bradykinin B1 receptor antagonist with a pA2 of 8.49 and no activity at B2 receptors. R 715 is metabolically stable and can reduce mechanical hypernociception in a mouse model of neuropathic pain.
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Additional information
| Three Letter Sequence | Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D?Nal-Ile-OH |
|---|---|
| Molecular Weight | 1140,4 |
| Molecular Formula | C57H81N13O12 |
| Sequence | KRPPGFSXI |
| Solubility | Soluble to 5 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | Lys-1 is N-terminal Acetyl, X is D?Nal |
| Searchable Words | R 715, bradykinin B1, antagonist, hypernociception, neuropathy, pain, Ac-KRPPGFS-D?Nal-I-OH, Ac-KRPPGFS-D?Nal-I-OH, 185052-09-9, KRPPGFSXI, R715, PN-070, PN070 |