R 715
£145.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Bradykinin B1 receptor antagonist.
R 715 is a potent and selective bradykinin B1 receptor antagonist with a pA2 of 8.49 and no activity at B2 receptors. R 715 is metabolically stable and can reduce mechanical hypernociception in a mouse model of neuropathic pain.
Please contact us for availability.
Additional information
| Three Letter Sequence | Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D?Nal-Ile-OH |
|---|---|
| Molecular Weight | 1140,4 |
| Molecular Formula | C57H81N13O12 |
| Sequence | KRPPGFSXI |
| Solubility | Soluble to 5 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | Lys-1 is N-terminal Acetyl, X is D?Nal |
| Searchable Words | R 715, bradykinin B1, antagonist, hypernociception, neuropathy, pain, Ac-KRPPGFS-D?Nal-I-OH, Ac-KRPPGFS-D?Nal-I-OH, 185052-09-9, KRPPGFSXI, R715, PN-070, PN070 |