Human Platelet Lysate (hPL) is a cell culture growth supplements obtained from human platelets. HPL contains abundant growth factors and cytokines necessary for cell growth and proliferation. Replacing foetal bovine serum (FBS) with hPL allows for expansion and potential clinical grade production of functional mesenchymal stromal cells by removing the risk of xenogeneic immune reactions and transmission of bovine prion and viral pathogens.
European guidelines require that bovine material should be removed from culturing media wherever possible for any therapeutic product containing cultured cells. hPL is a suitable alternative for use in R&D and production / manufacturing processes.
