Human Platelet Lysate (HPL)
Human Platelet Lysate (hPL) is a cell culture growth supplements obtained from human platelets. HPL contains abundant growth factors and cytokines necessary for cell growth and proliferation. Replacing foetal bovine serum (FBS) with hPL allows for expansion and potential clinical grade production of functional mesenchymal stromal cells by removing the risk of xenogeneic immune reactions and transmission of bovine prion and viral pathogens.
European guidelines require that bovine material should be removed from culturing media wherever possible for any therapeutic product containing cultured cells. hPL is a suitable alternative for use in R&D and production / manufacturing processes.
Human Platelet Lysate (HPL) products:
ELAREM™ products. HPL from Research to GMP Grade. Some require the addition of heparin prior to use. This product line includes ELAREM Prime, Perform, Perform-FD, Ultimate-FDi and Matrix Kit.
Xeno Free hPL
A completely xeno-free (animal-component free), fibrinogen-depleted hPL. No heparin supplementation required. For human ex-vivo tissue and cell culture processing applications.