Human Platelet Lysate - more details

Key Benefits

  • Pooled from multiple donors - the consistent supply of donor platelets helps to stabilize availabilty and pricing.
  • A standardized, qualified product which is manufactured to reduce batch-to-batch variation.
  • Human-derived (animal-protein free) product which has been subject to extensive serology testing ensures safety for each batch.
  • GMP-Clinical grade product is manufactured under GMP compliant conditions using high quality raw materials and GMP compliant cell culture SOPs.
  • Available in three formats depending on application needs:
    • Standard heparin needs to be added before use.
    • Fibrin-depleted – no heparin supplementation required but residues of heparin may remain. Available as both Research and GMP Grade material.
    • Xeno-free – a completely xeno-free, fibrin-depleted hPL. No heparin supplementation required. Available as both Research and GMP Grade material.


  • Human Platelet Lysate can be used as a replacement for traditional foetal bovine supplemented cell culture medium.
  • HPL is a suitable alternative for use in R&D and production/ manufacturing processes.
  • Improves the proliferation of Mesenchymal Stromal Cells (MSCs) compared to FBS without loss of phenotype.
  • Read other examples of how hPL has been used in research applications.

Quality assured

  • HPL is derived from human donor platelets collected from healthy consented volunteer donors at certified German Blood banks (21CFR640)
  • All batches are fully tested for pathogens according to FDA guidelines and found non-reactive for HBsAg, HIV I/II antibody, CMV, HCV- and HBC-Antibody, HIV-, HCV-, HBV-, HAV-, PVB19-NAT, Syphilis and Treponema pallidum.
  • Each batch is filtered to 0.1 micron before being dispensed, aspectically, into either bottles or cryo-bags.
  • Each batch of hPL is tested for the absence of bacteria, fungi, yeast and Mycoplasma. In addition, biological performance of final batches is assessed by cell culture on MSC, Fibroblasts and Primary cells.
  • Full batch documentation is available, including Certificates of Analysis.

To order

We can accept orders online and by telephone on 01234 889180 or e-mail

HPL is supplied in 100mL bottles. PL Solution, GMP Grade (PLS-002) can also be supplied in CryoBags on request.


For research use only. Not for therapeutic or diagnostic use.

Despite all testing, proper safety precautions for potentially infectious agents must be taken. All human blood products should be handled in accordance with currently acceptable biosafety practices and guidelines for the prevention of blood borne viral infections.

Human Platelet Lysate (HPL) products: