PR 39
£275.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Cathelicidin host defence and immunomodulatory peptide.
PR 39 is a 39 amino acid proline-rich cathelicidin host defence and immunomodulatory peptide isolated from porcine polymorphonuclear neutrophils. PR 39 plays a pivotal role in the innate immune defence of the pig against infections. Besides direct antimicrobial activity, PR 39 is involved in wound healing and also stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκB.
Please contact us for availability.
Additional information
| Three Letter Sequence | H-Arg-Arg-Arg-Pro-Arg-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Pro-Phe-Phe-Pro-Pro-Arg-Leu-Pro-Pro-Arg-Ile-Pro-Pro-Gly-Phe-Pro-Pro-Arg-Phe-Pro-Pro-Arg-Phe-Pro-NH2 |
|---|---|
| Molecular Weight | 4719.7 |
| Molecular Formula | C229H346N70O40 |
| Sequence | RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2 |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | H-RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2, RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2, 139637-11-9, PR 39 , cathelicidin, immunomodulatory, wound healing, angiogenesis, PR39, AM-110, AM110 |