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PR 39

£275.00 1mg

SKU: AM-110 Categories: ,

Cathelicidin host defence and immunomodulatory peptide.

PR 39 is a 39 amino acid proline-rich cathelicidin host defence and immunomodulatory peptide isolated from porcine polymorphonuclear neutrophils. PR 39 plays a pivotal role in the innate immune defence of the pig against infections. Besides direct antimicrobial activity, PR 39 is involved in wound healing and also stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκB.

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Additional information

Three Letter Sequence

H-Arg-Arg-Arg-Pro-Arg-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Pro-Phe-Phe-Pro-Pro-Arg-Leu-Pro-Pro-Arg-Ile-Pro-Pro-Gly-Phe-Pro-Pro-Arg-Phe-Pro-Pro-Arg-Phe-Pro-NH2
Molecular Weight

4719.7
Molecular Formula

C229H346N70O40
Sequence

RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2
Solubility

Soluble in dilute acid
Appearance

Freeze dried solid
Storage

Store desiccated, frozen and in the dark
Purity

>95% by HPLC
Modifications

C terminal amide
Searchable Words

H-RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2, RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2, 139637-11-9, PR 39 , cathelicidin, immunomodulatory, wound healing, angiogenesis, PR39, AM-110, AM110