PR 26

£195.00 1mg

Antimicrobial.

PR 26 is the first 26 amino acid residues of the amine terminus of the functional antimicrobial domain of PR 39 (AM-110), the proline-rich cathelicidin host defence and immunomodulatory peptide isolated from porcine polymorphonuclear neutrophils. PR 26 is as least as potent as PR 39 against enteric gram negative bacteria and potentiates neutrophil phagocytosis of Salmonella choleraesuis and decreases the level of S. typhimurium invasion into intestinal epithelial cells, however PR 26 does not lyse cells by pore-forming mechanisms.

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SKU: AM-111 Categories: ,

Additional information

Three Letter Sequence

H-Arg-Arg-Arg-Pro-Arg-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Pro-Phe-Phe-Pro-Pro-Arg-Leu-Pro-Pro-Arg-Ile-OH

Molecular Weight

3229.9

Molecular Formula

C153H242N50O28

Sequence

RRRPRPPYLPRPRPPPFFPPRLPPRI

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store dry, frozen and desiccated

Purity

>95% by HPLC

Searchable Words

H-RRRPRPPYLPRPRPPPFFPPRLPPRI-OH, RRRPRPPYLPRPRPPPFFPPRLPPRI, PR 26, cathelicidin host defence, immunomodulatory, PR26, PR-26, AM-111, AM111