PKA Inhibitor (6-22) Amide

£65.00 1mg

cAMP-dependent protein kinase (PKA) inhibitor.

PKA inhibitor (6-22) amide, also known as PKI(6-22) amide, is an inhibitor of cAMP-dependent protein kinase (PKA). PKA Inhibitor (6-22) amide is derived from the active section of the heat-stable PKA inhibitor PKI, the endogenous PKA inhibitor protein, and is the shortest synthetic PKI peptide with high potency for PKA inhibition. PKA inhibitor (6-22) amide inhibition of PKA can decrease long-term potentiation (LTP) at hippocampal synapses and reverse morphine tolerance.

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SKU: KS-060 Categories: ,

Additional information

Other Names

PKI(6-22) amide

Three Letter Sequence

H-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2

Molecular Weight

1868.1

Molecular Formula

C80H130N28O24

Sequence

TYADFIASGRTGRRNAI-NH2

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Modifications

C terminal amide

Searchable Words

TYADFIASGRTGRRNAI-NH2, TYADFIASGRTGRRNAI, 121932-06-7, PKA inhibitor (6-22) amide, PKI(6-22) amide, cAMP-dependent protein kinase , PKA, KS-060, KS060