PKA inhibitor (6-22) amide
£65.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
cAMP-dependent protein kinase (PKA) inhibitor.
PKA inhibitor (6-22) amide, also known as PKI(6-22) amide, is an inhibitor of cAMP-dependent protein kinase (PKA). PKA Inhibitor (6-22) amide is derived from the active section of the heat-stable PKA inhibitor PKI, the endogenous PKA inhibitor protein, and is the shortest synthetic PKI peptide with high potency for PKA inhibition. PKA inhibitor (6-22) amide inhibition of PKA can decrease long-term potentiation (LTP) at hippocampal synapses and reverse morphine tolerance.
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Additional information
| Other Names | PKI(6-22) amide |
|---|---|
| Three Letter Sequence | H-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2 |
| Molecular Weight | 1868.1 |
| Molecular Formula | C80H130N28O24 |
| Sequence | TYADFIASGRTGRRNAI-NH2 |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | TYADFIASGRTGRRNAI-NH2, TYADFIASGRTGRRNAI, 121932-06-7, PKA inhibitor (6-22) amide, PKI(6-22) amide, cAMP-dependent protein kinase , PKA, KS-060, KS060 |