Phosphoramidon Disodium

£85.00 5mg

Metalloendopeptidase inhibitor.

Phosphoramidon is a metalloendopeptidase inhibitor originally derived from cultures of Streptomyces tanashiensis. Phosphoramidon is a potent inhibitor of thermolysin and other metallo-endopeptidases and also strongly inhibits mammalian enkephalinase but does not inhibit trypsin, papain, chymotrypsin or pepsin. Phosphoramidon has been used as a neprilysin (NEP) inhibitor to study amyloid beta (A?) uptake and degradation.

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SKU: PI-130 Categories: ,

Additional information

Three Letter Sequence

N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan

Molecular Weight

587.47

Molecular Formula

C23H32N3O10P¢2Na

Sequence

LW

Solubility

50 mg per ml in water

Appearance

Off white powder

Storage

Store desiccated, frozen and in the dark

Purity

‰¥97% (HPLC)

Modifications

N-(α-Rhamnopyranosyloxyhydroxyphosphinyl at N terminal