PACAP 38
£185.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Endogenous PAC1 receptor agonist.
PACAP 38, or Pituitary adenylate cyclase activating polypeptide-38, is a widely distributed endogenous neuropeptide located in both sensory and parasympathetic perivascular nerve fibes. PACAP 38 acts primarily as a PAC1 agonist and is involved in neuroprotection, neurodevelopment, nociception and inflammation. PACAP 38 is a potent inducer of migraine like attacks in migraineurs and headache in non migraineurs.
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Additional information
| Other Names | Pituitary Adenylate Cyclase-Activating Polypeptide 1-38, PACAP 1-38 |
|---|---|
| Three Letter Sequence | H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 |
| Molecular Weight | 4534.32 |
| Molecular Formula | C ‚‚ ‚ ‚ƒH ‚ƒ ‚ƒ ‚N ‚† ‚ƒO ‚… ‚ƒS |
| Sequence | HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH ‚‚ |
| Solubility | Soluble to 0.90 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | 95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | PACAP 38, PACAP38, HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH ‚‚, HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK, 124123-15-5 |