PACAP 38
£185.00 1mg
Endogenous PAC1 receptor agonist.
PACAP 38, or Pituitary adenylate cyclase activating polypeptide-38, is a widely distributed endogenous neuropeptide located in both sensory and parasympathetic perivascular nerve fibes. PACAP 38 acts primarily as a PAC1 agonist and is involved in neuroprotection, neurodevelopment, nociception and inflammation. PACAP 38 is a potent inducer of migraine like attacks in migraineurs and headache in non migraineurs.
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Additional information
| Other Names | Pituitary Adenylate Cyclase-Activating Polypeptide 1-38, PACAP 1-38 |
|---|---|
| Three Letter Sequence | H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 |
| Molecular Weight | 4534.32 |
| Molecular Formula | C ‚‚ ‚ ‚ƒH ‚ƒ ‚ƒ ‚N ‚† ‚ƒO ‚… ‚ƒS |
| Sequence | HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH ‚‚ |
| Solubility | Soluble to 0.90 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | 95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | PACAP 38, PACAP38, HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH ‚‚, HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK, 124123-15-5 |